The accident happened on Belgrave Middleway in Birmingham at about 01:00 GMT and involved six vehicles.
The driver of a black cab died at the scene near Edgbaston, along with a female passenger, while a male passenger died later in hospital.
Four men in a car were all thrown from their vehicle and three of them died at the crash site. The fourth is in a critical condition.
West Midlands Police described the scene as “very difficult and upsetting” and the stretch of road from Islington...